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Chemotherapy Biotherapy Certification Questions with Correct Answers.
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Chemotherapy Biotherapy Certification Questionswith Correct Answers
Resources Correct Ans ✓✓ nccn.org
cancer.org
LESSON 1: Cell cycle Correct Ans ✓✓ g1- increase in size
s- dna replicated
g2- cell enlarge and ready to divide
m phase- 2 hours
mitosis Correct Ans ✓✓ 4 stages, prophase, metaphase, anaphase,
telophase
-chemo targets certain points in the process
apoptosis Correct Ans ✓✓ programmed cell death
hematopoiesis Correct Ans ✓✓ formation of blood cells & how cells
differentiate
-myeloid: pre cells mature into RBCs, platelets and WBCs
-lymphoid: pre cells- mature into WBCS
Principles of Biotherapy: p51-95 immunology Correct Ans ✓✓ -defense
against foreign organisms, homeostasis (destroy aged cells), surveillance
,immune responses Correct Ans ✓✓ innate: primary line of defense, non
specific, no memory
adaptive: secondary line of defence with specific memry
cytokines Correct Ans ✓✓ -effect growth and differentiation of WBC
-interferons, tumor necrosis factors, growth factos and interleukins
-small protein molecules released by cells throughout body providing
comunication between cells of the immune system
-regular antiboddy production and function of b cells
vaccines for cancer prevention Correct Ans ✓✓ -hep B prevents
hepatitis and hepatocellular carcinoma
-hpv vaccine
filgrastim aka neupogen Correct Ans ✓✓ SC or IV to derease infection
in patients with neutropenic fever associated with myelosuppressive
anticancer treatments for nonmyeloid malignancies
tbo-filgramstim/ pegfilgrastim Correct Ans ✓✓ reduce duration of
neutroenia in patients with non myeloid malignancies
palifermin Correct Ans ✓✓ IV to dec incidence of oral mucositis in
patients with hem malignanies before BMT
, sargramostim Correct Ans ✓✓ aka leukine - patients with AML
following chemo to shorten neutrophil recovery and reduce incidence of
infection
IFN gamma Correct Ans ✓✓ reduce frequency and severity o infections
related to granulomatous disease
aldeleukin Correct Ans ✓✓ treat renal cell carcinoma and metastatic
melanoma
oprevelkin Correct Ans ✓✓ prevent severe thrombocytopenia and
refuce need for platelet transfusions in patients with nonmyeloid malig
plerixafor Correct Ans ✓✓ with filgrastim to mobilize hematopoeitc
stem cells for collection from peripheral blood of patients
sipuleucel Correct Ans ✓✓ castrate resistant prostate cancer
rituximab Correct Ans ✓✓ rituxan- treatment of relapsed or refractory
low grade follicular b cell NHL_ first line traetment in combo with
chemo in patients with response
-can treat severe rheumatoid arthritis
-can have severe reactions (hypotension, urticaria, angiodema, hypoxia,
rigors, dyspnea, chills, fever, nausea, rash, renal tox)
-premed with tylenol and benadryl
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