100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Previously searched by you
Previously searched by you
logo
HMX-Pharmacology Questions With Answers Graded A+ Assured Success R151,17
Add to cart
Quickly navigate to
Preview
  2.  
  3. HMX-Pharmacology
  4.  
  5. HMX-Pharmacology

Exam (elaborations)

HMX-Pharmacology Questions With Answers Graded A+ Assured Success
 0 purchase
  • Course
  • HMX-Pharmacology
  • Institution
  • HMX-Pharmacology

bladder - All filtrated by nephrons will be transported through the collecting duct into the renal pelvis, draining filtrate out of the kidney into the ureter. Next, the filtrate enter the _________ and is removed from the body Acetaminophen (Tylenol) - binds to molecular target in the central n...

[Show more]

Preview 4 out of 41  pages

Document information

  • August 20, 2024
  • 41
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

Subjects

  • hmx pharmacology

Written for

  • HMX-Pharmacology
  • HMX-Pharmacology

Seller

avatar-seller
PatrickKaylian

Reviews received

Content preview

HMX-Pharmacology
bladder - All filtrated by nephrons will be transported through the collecting duct into the renal
pelvis, draining filtrate out of the kidney into the ureter. Next, the filtrate enter the _________ and is
removed from the body



Acetaminophen (Tylenol) - binds to molecular target in the central nervous system and changes
the way the body senses pain



% molecular response vs concentration - Gradual increase which moves into a due plateau

Receptor occupancy is used to determine molecular response

Taken in a lab setting

This Is called a dose-response curve (DRC)



%Physiological response or % people responding vs dose of drug administered - In a clinical
setting

Gradual increase which moves into a due plateau

This called a drc: linear seal



%Physiological response or % people responding vs dose of drug administered - Plotted on a x log
scale

Can also show concentration of drug at molecular target vs molecular response

x=dose

Semi log plot

In a clinical setting

Curve is more compared and in sigmoidal shape

A range of dose



100% - If administrated intravenously, bioavailability is ___

,1800 - Diabetes=A child was expected to live only past a year after diagnosis

Symptoms found:

Weakness

Excessive urination

Sweet tasting urine

Constant thirst



38L - An adult male has 3L of plasma and ___ of other compartments (inerstitial, intracellular,
transcellular, fat)



38L - Other body compartment including bone, muscle and fat with ____



3L - An adult male has __ of plasma and 38L of other compartments (inerstitial, intracellular,
transcellular, fat)



41L - If Vd is higher than the total ____ body water volume in an average man, Vd is considerably
high



5L - Vascular includes the blood, with a ___



70 kg - The model for pharmacokinetics is male weighing _____



Absorption - as a drug is taken orally and flows through the esaphagus and into the GIT
(gestational tract)



Absorption - The flow of a drug from its site of administration to the bloodstream



Absorption - the movement of drug from the site of administration to the bloodstream

,Absorption - the movement of the site of administration to the bloodstream



afferent arteriole - Plasma enter the nephron via



affinity - Low selectivity = increase kd=low _______



Affinity - measure of the strength of drug-receptor bind and is indicated by the equilibrium
dissociation constant, or Kd



age, genetics, weight, sex, health status, and pregnancy - Factors which lead to pharmacokinetic
or pharmodynmics changes between individuals or in an individual over time include
_________________



agonist, antagonist - A drug or endogenous ligand can act act as _______ or an ___________ at a
receptors



Allogenic - T cell are created by patients own cell but engineered to help with any possible disease
presented in the body



anaphylactic shock - Immunological reaction can be immediate, patient goes into _____



Anesthesia - Induction of an awake to unconscious state



Antagonist - Stagnant or straight line

Does Not increase of decrease downward signal(molecular response)



antagonist - zero efficacy



Area under curve (AUC) - On graph, show the total exposure of drug to the body

, Basal - Submaximal

Stagnant or straight line



binding curve - Gradual increase which moves into a plateau due to maximum occupancy



Bioavailability - A large fraction of drug in the system circulation which create a high percentage



Bioavailability - Plasma drug/drug given



bioavailable - the amount of drug that is available in the systemic circulation



Biologics - Biological molecules = _________



Biologics - From natural sources

Growing group of drug modalities

Are less than 20% of the drugs on the market

Larger due to being complex structures



Biologics - Includes vaccines, proteins, antibodies, probiotics, and gene- and cell-based therapies



biotransformation - Through __________, drugs are metabolized into metabolites



blood vessel - If a drug is taken under the tongue, it is moved directly into the _____________ to
bypass the G1 tract. Drugs like nitroglycerin take this path



Blood- brain barriers - are is protection outside the brain have endothelial cell tight pactly
together

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through EFT, credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying this summary from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller PatrickKaylian. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy this summary for R151,17. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

68175 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy summaries for 15 years now

Start selling
R151,17
  • (0)
Add to cart
Added