Cell migration - Answer-cells move to final locatin. Double band cortex occurs if cell
migration doesn't happen correctly
Problems: genetic disease
Differentiation - Answer-cells become distinctive neurons/glial cell
Problems: Astrocytoma
Synaptogenesis - Answer-establishment of synaptic connections
Problems: Autism
Neuronal cell death - Answer-selective death of some nerve cells
Problems: Fragile X syndrome (neurons unable to be pruned off -> enlarged head)
Synapse rearrangement - Answer-loss/growth of synapses, fine-tuning
-only life long process, other 5 stages only occur in womb
Neurogenesis (analogy) - Answer-Need bricks, *brick factory* to make all of these
bricks for a house.
Cell Migration (analogy) - Answer-After bricks are made, need to be shipped to where
they will be built
Differentiation (analogy) - Answer-Sorting out what building supplies go where and what
their function will be
Synaptogenesis (analogy) - Answer-put bricks together end to end in right order to form
wall. Establishing connection here
,Neuronal cell death (analogy) - Answer-Now have walls but need doors & windows,
need to knock out sections of brick for this
-selective death of neurons
Synapse rearrangement (analogy) - Answer-Finally house is going to be
remodeled/added to over the years
-fine tuning & lifelong in brain
Neuron doctrine - Answer-1. Brain composed of independent cells
2. Signal transmitted from cell to cell across gaps (synapses)
3. Santiago Ramón y Cajal proposed neuron doctrine
-used Golgi's cell staining method
astrocytes - Answer-GLIAL CELL
supportive cells in brain that fills in spaces
-store, absorb, release chemicals
-most numerous glial cell in CNS
microglia - Answer-GLIAL CELL
clean up dying neurons & glia
-PHAGOCYTES
-brain & spinal cord only
ependymal cells - Answer-GLIAL CELL
PHASE 1: *guiding* embryonic cells during development
PHASE 2: *lining ventricles* & secreting CSF
-VENTRICULAR SYSTEM
oligodendryocytes - Answer-GLIAL CELL
Wraps around many axons in order to coat them with myelin sheaths in CNS
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