Molecular Cell Biology PCB 3023 BROWARD COLLEGE/ UNIVERSITY of
SOUTH FLORIDA/ UCF COLLEGE Of Sciences
Why do lipids self-assemble in water? - Answer✔️✔️-To prevent
hydrophobic tails from touching water. Hydrophillic heads protect.
This lowers free energy (delta G).
If hydrophillic heads are exposed... - Answer✔️✔️-Delta G will
increase
Glycolipids - Answer✔️✔️-lipid with glycosidic bond to glucose in
hydrophillic head.
Antigens on Red Blood Cells are..? - Answer✔️✔️-Glycolipids
Cholesterol - Answer✔️✔️-A lipid steroid ring attached to glycerol.
Fills gaps in Plasma Membrane left by unsaturated hydrocarbon
tails. Rigid.
How many pints of Blood are in the body? - Answer✔️✔️-10 pints, on
average. When you donate blood you donate a pint. 7,000,000,000
RBCs in a single liter. Body has trillions of cells
What is Fluidity? - Answer✔️✔️-How easily lipids can move within a
membrane
What is Fluidity dependent on? - Answer✔️✔️-Temperature (if
decreased, membrane becomes gel-like)
Are cells symmetrical or asymmetrical? - Answer✔️✔️-Asymmetrical.
Asymmetry established at 'birth' of the cell
What is flipase? - Answer✔️✔️-Specific catalyzed Transfer. Uses fatty
acids from cytosolic monolayer to add new membrane. Responsible
for 'flip-flop' of lipids
What is scramblase? - Answer✔️✔️-Random Catalyzed Transfer.
Where are lipids synthesized? - Answer✔️✔️-Endoplasmic Reticulum.
How are lipids synthesized in the ER transported across the cell? -
Answer✔️✔️-Via vesicles.
(EXCEPTION: Lipids for Mitochondrial Membrane and Plasmid
Membrane)
Why are cells asymmetrical? - Answer✔️✔️-1. To distinguish living
and dead cells (Phosphatadylserine (-) is transferred across
membrane during apoptosis)
2. Signal Transduction. So that extracellular signals can be relayed
through cell membrane
Types of Movement in Membrane Lipids - Answer✔️✔️-1. Lateral
Diffusion (~10^8 cm^2/sec at 310K)
2. Transverse Fluctuation
3
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