Hematology BOC Questions Ch 21-28 Exam With All Verified Solutions.
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Course
BOC Hematology
Institution
BOC Hematology
Which of the following findings is consistent with a diagnosis of megaloblastic anemia? - Answer Increase MCV
A patient has a clinical picture of megaloblastic anemia. The serum folate level is decreased, and the serum vitamin B12 level is normal. What is the expected value for the methylmalo...
Hematology BOC Questions Ch 21-28
Exam With All Verified Solutions.
Which of the following findings is consistent with a diagnosis of megaloblastic anemia? - Answer
Increase MCV
A patient has a clinical picture of megaloblastic anemia. The serum folate level is decreased, and the
serum vitamin B12 level is normal. What is the expected value for the methylmalonic acid assay? -
Answer Normal
Which one of the following statements characterizes the relationship among macrocytic anemia,
megaloblastic anemia and pernicious anemia - Answer Megloblastic anemia is macrocytic
Which of the following CBC findings is most suggestive of megaloblastic anemia? - Answer
Hypersegmentation of neutrophils
Which of the following findings would be inconsistent with elevated titers of parirtal cells antibodies? -
Answer Low levels of methylmalonic acid
Which of the following is the most metabolically active form of absorbed vitamin b 12? - Answer
Holotranscobalamin
Folate and vitamin b 12 work together in the production of - Answer DNA
The macrocytosis associated with megaloblastic anemia result from - Answer reduced numbers of cell
divisions
Individuals of which one of the following groups are at higher risk for pernicious anemia? - Answer
Person older than 60 years of age
The clinical consequence of pancytopenia include - Answer Fatigue, infection, and bleeding
, Idiopathic acquired aplastic anemia is due to - Answer unknown cause
The pathophysiologic mechanism in acquired idiosyncratic aplastic anemia is - Answer Destruction of
stem cells by autoimmune T cells
Aplastic anemia claasification of a patient with bone marrow celluarity of 10% an Hb of 7g/dl, and
absolute neutrophil count of .01 x10 to9/l a platelet count of 10x 10to 9/ l - Answer very severe
The most consistent periphertal blood findings in severe aplastic anemia are - Answer Macrocytosis,
thrombocytopenia, and neutropenia
The treament that has shown the best success rate in young patiens with severe aplastic anemis is -
Answer stem cell transplant from HLA identical sibling
The test that is most useful indiferentiating Fa from other causes of pancytopenia is - Answer DEB-
induced chromosome breakage
Mutation in genes that code for the telomerase complex may induce bone marrow failure by causing
which of the following? - Answer Premature death of stem cells
DBA differs fron inherited aplastic anemia in that in the former - Answer Only erythropoesis is affected
Which anemia ishould be suspected in a patient with refractory anemia reticulocytopenia,
hemosiderosis, and binucleated erythrocyte precursors in the bone marrow - Answer Congenital
dyserythropoietic anemia
The primary pathophysiologic mechanism of anemia of chronic kidney disease is - Answer Inadequate
production of erthropoietin
The term hemolytic disorder in general refers to a disorder in which there is - Answer Increases
destruction of rbc after they enter the blood stream
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