TEST BANK
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Test Bank for Oral Histology & Embryology, 5th Edition
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, Daniel J. Chiego: Essentials of Oral Histology and Embryology-A Clinical
Approach
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Chapter 01: Development and Structure of Cells and Tissues
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MULTIPLE CHOICE
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1. Mitochondria produce which chemical for intracellular energy?
a. ADP
b. ATP
c. RNA
d. DNA
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ANS: B
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Feedback
A Mitochondria generate energy through ATP, not ADP, production.
B Correct. Mitochondria produce energy via ATP.
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C Mitochondria generate energy through ATP, not RNA, production.
D Mitochondria generate energy through ATP, not DNA, production.
DIF: Recall REF: pp. 2-3 OBJ: 1
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2. Each tissue originates from mesoderm, EXCEPT one. Which is the EXCEPTION?
a. Bone
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b. Liver
c. Blood
d. Muscle
ANS: B
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Feedback
A Bone tissue develops from mesodermal cells.
B Correct. Liver tissue is produced by endodermal cells.
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C Blood develops from mesodermal cells.
D Muscle tissue develops from mesodermal cells.
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DIF: Recall REF: p. 6 OBJ: 3
3. Which chemical is called the second messenger?
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a. aDNA
b. mRNA
c. dGMP
, d. cAMP
ANS: D
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Feedback
A cAMP is the second messenger; aDNA is not.
B cAMP is the second messenger; mRNA is not.
C cAMP is the second messenger; dGMP is not.
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D Correct. cAMP transmits information to the intracellular organelles when
activated by surface receptors on the plasma membrane.
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DIF: Recall REF: p. 3 OBJ: 3
4. Which cellular component facilitates protein synthesis?
a. Ribosomes
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b. Lysosomes
c. Mitochondria
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d. Plasmalemma ANS: A
Feedback
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A Correct. Ribosomes synthesize protein.
B Lysosomes facilitate the breakdown of intracellular and extracellular substances.
C Mitochondria generate energy.
D The plasmalemma provides a protective barrier and regulates the transport of
substances to and from the cell.
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5. Which organelle produces microtubules?
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a. Nucleus
b. Centriole
c. Golgi apparatus
d. Endoplasmic reticulum ANS: B
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Feedback
A Centrioles generate microtubules; the nucleus does not.
B Correct. Centrioles produce microtubules.
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C Centrioles generate microtubules; the Golgi apparatus does not.
D Centrioles generate microtubules; the endoplasmic reticulum does not.
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DIF: Recall REF: p. 3 OBJ: 1
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6. Which phase of the cell cycle is characterized as the initial resting stage?
, a. S phase
b. G1 phase
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c. G2 phase
d. Prophase ANS: B
Feedback
A The S phase is characterized as the stage in which DNA synthesis is complete.
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B Correct. The G1 phase is the initial resting stage.
C The G2 phase is characterized by post-DNA duplication.
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D Prophase is characterized by four specific structural changes.
DIF: Recall REF: p. 4 OBJ: 1
7. Posttranslational modifications to proteins produced by the rough endoplasmic reticulum
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are
accomplished by .
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a. mitochondria
b. Golgi apparatus
c. messenger RNA
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d. smooth endoplasmic reticulum ANS: B
Feedback
A The Golgi apparatus is responsible for posttranslational alterations; mitochondria
are not.
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B Correct. The Golgi apparatus makes alterations to proteins produced by the
rough endoplasmic reticulum.
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C The Golgi apparatus is responsible for posttranslational alterations; mRNA is
not.
D The Golgi apparatus is responsible for posttranslational alterations; the smooth
endoplasmic reticulum is not.
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DIF: Recall REF: p. 2 OBJ: 1
8. The provides an ideal environment for the implantation and growth of the embryo.
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a. ovary
b. uterine tube
c. myometrium
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d. endometrium ANS: D
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Feedback
, A The ovary is the female reproductive organ, in which the ova or eggs are
produced.
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B The uterine tube conducts the egg from the ovary to the uterus.
C The myometrium is the smooth muscle that lines the uterus.
D Correct. The endometrium provides the ovum with the nourishment necessary
for implantation and growth.
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9. Intercalated disks are present in which type of muscle?
a. Cardiac
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b. Smooth
c. Skeletal
d. Voluntary ANS: A
Feedback
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A Correct. Cardiac is the only type of muscle tissue with intercalated disks.
B Intercalated disks are not present in smooth muscle.
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C Intercalated disks are not present in skeletal muscle.
D Intercalated disks facilitate the involuntary contractions of cardiac muscle.
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DIF: Recall REF: p. 15 OBJ: 4
10. Developmental abnormalities are not associated with which number of chromosomes?
a. 44
b. 45
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c. 46
d. 47
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ANS: C
Feedback
A Developmental abnormalities are associated with less than the normal number of
chromosomes (46).
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B Developmental abnormalities are associated with less than the normal number of
chromosomes (46).
C Correct. The normal human cell has 46 total chromosomes.
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D Developmental abnormalities are associated with more than the normal number
of chromosomes (46).
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DIF: Comprehension REF: p. 16 OBJ: 4
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11. Which best describes diapedesis?
, a. Programmed cell death and fragmentation
b. A protective mechanism in the immunologic defense of the body
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c. The development of a cartilage disk in the neck of each long bone
d. The migration of leukocytes between endothelial cells to the site of infection ANS: D
Feedback
A Apoptosis is cell death and fragmentation into membrane-bound particles.
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B The lymphatic system is an immunologic defense mechanism.
C The epiphyseal plate is a developmental disk of cartilage.
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D Correct. Diapedesis is a process whereby leukocytes migrate between
endothelial cells to the site of infection.
DIF: Comprehension REF: p. 12 OBJ: 4
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12. T cells, B cells, NK cells, and macrophages are produced in the .
a. spleen
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b. cerebellum
c. lymph nodes
d. bone marrow ANS: D
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Feedback
A Immune system cells (T cells, B cells, NK cells, and macrophages) are produced
in the bone marrow, not the spleen.
B Immune system cells (T cells, B cells, NK cells, and macrophages) are produced
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in the bone marrow, not the cerebellum.
C Immune system cells (T cells, B cells, NK cells, and macrophages) are produced
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in the bone marrow, not the lymph nodes.
D Correct. Bone marrow is the site of formation for T cells, B cells,
NK cells, and macrophages.
13. Which represent the first change in shape of the embryo’s body from a flat sheet of cells?
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a. Formation of the embryonic disk.
b. Formation of neural folds.
c. Formation of cartilage.
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d. Migration of myoblasts from the myotome. ANS: B
Feedback
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A The embryonic disk forms from a small inner cell mass within the blastocyst. This occurs
prior to the formation of the three primordial layers, long before the
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embryo acquires a three-dimensional shape.
, B Correct. The neural folds can be seen during the third prenatal week.
The lateral
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edges of the neural plate begin to elevate as folds arise dorsally.
C Cartilage first appears in the fifth week.
D Muscle cells have begun migrating from the myotome by the 10th prenatal
week.
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DIF: Comprehension REF: pp. 10-11 OBJ: 3
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14. Myotome produces which of the following types of tissue?
a. Connective
b. Muscle
c. Nerve
d. Epithelial ANS: B
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Feedback
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A Connective tissue develops from somites as fibroblasts migrating from either
side of the neural tube.
B Correct. Myoblasts have begun migrating from the myotome by the 10th
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prenatal week. They gradually differentiate into elongated, multinucleatedmuscle fibers.
C Nerve is derived from both the cranial and trunk neural crest. When the anterior
neural tube closes, it shows three dilations that form the primary brain vesicles.
D Skin has an epidermis, a surface cell layer that develops from the surface of
ectodermal cells, and a dermis, which arises from the underlying mesoderm.
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DIF: Comprehension REF: p. 15 OBJ: 3
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15. Which type of bone formation occurs through a tight matrix of collagen fibers, which
slowly calcify into bone?
a. Endochondral
b. Intramembranous
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c. Epiphyseal
d. Interstitial growth ANS: B
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Feedback
A Bone replaces cartilage during endochondral bone development. A small bloodvessel
enters the cartilage shaft, the cartilage calcifies and disintegrates in the
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center, and a marrow space is formed.
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, Oral Histology and Embryology 5th edition Chiego 8
B Correct. Intramembranous bone formation is the direct transformation of connective
tissue into bone. It is much simpler for bone cells to organize in thismanner and to form spicules
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of bone through coalescence with neighboring
spicules until a bony plate is formed.
C The epiphyseal plate is a developing cartilage disk that remains in the neck of
each long bone and bone forms on either side. It will remain as long as the boneis forming.
D Cartilage develops and expands by interstitial growth, which is growth within the
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cartilage matrix by each cartilage cell enlarging and forming matrix around
each cell.
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16. Blood cells arise from cells called
a. neuroblasts.
b. fibroblasts.
c. osteoblasts.
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d. angioblasts. ANS: D
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Feedback
A Neuroblasts are primitive nerve cells that develop into adult neurons.
B Connective tissue develops from the somites as fibroblasts migrating from either
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side of the neural tube.
C Osteoblasts will form bone.
D Correct. The cardiovascular system originates from cells termed angioblasts, which arise
from angiogenic clusters from the visceral mesoderm located in the walls of the yolk sac during
the third week.
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The outer cells organize into a series
of elongating tubes and the inner cells become blood cells.
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DIF: Recall REF: p. 15 OBJ: 3
17. Each of the following is a derivative of ectoderm EXCEPT one. Which is the
EXCEPTION?
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a. Tooth enamel
b. Tooth dentin
c. Epidermis
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d. Nervous system ANS: B
Feedback
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A Tooth enamel is derived from ectoderm.
B Correct. Tooth dentin is derived from mesoderm. Muscle and connective tissue
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derivatives such as: bone, cartilage, blood, pulp, cementum, and the
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, Oral Histology and Embryology 5th edition Chiego 9
periodontalligament are also derived from mesoderm.
C The epidermis, hair, and nails are derived from ectoderm.
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D The nervous system, sensory epithelium of the eye, ear, and nose, and
epithelium of the sinuses, oral and nasal cavities, and intraoral
glands are allderived from epithelium.
DIF: Comprehension REF: p. 9 OBJ: 3
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18. Which hormone is produced by the placenta?
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a. Follicle-stimulating hormone (FSH)
b. Prolactin
c. Progesterone
d. Adrenocorticotropic hormone (ACTH) ANS: C
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Feedback
A Follicle-stimulating hormone (FSH) is secreted by the anterior lobe of the
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pituitary gland.
B Prolactin is produced by the anterior lobe of the pituitary gland.
C Correct. The placenta produces hormones such as human chorionic gonadotropin,
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placental growth factor, human placental lactogen,
andprogesterone and estrogen.
D Adrenocorticotropic hormone (ACTH) is produced by the anterior lobe of the
pituitary gland.
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DIF: Comprehension REF: p. 16 OBJ: 4
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TRUE/FALSE
1. The ovum contains twice as many chromosomes as its parent cell.
ANS: F DIF: Comprehension REF: p. 4OBJ: 1
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2. The cell may contain more than one nucleolus.
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ANS: T DIF: Recall REF: p. 2 OBJ: 1
3. The information in mRNA is translated by ribosomes located on the surface of the rough
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endoplasmic reticulum.
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ANS: T DIF: Comprehension REF: p. 2OBJ: 1
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