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Exam (elaborations)

PCOL Exam Questions And Accurate Answers

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PCOL Exam Questions And Accurate Answers...

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  • October 7, 2024
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  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • PCOL
  • PCOL
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PCOL Exam Questions And Accurate Answers


Drug Y will exhibit lesser therapeutic effect-ANSWER A patient is maintained on
medication with Drug X, which is known to be an enzyme inducer. Later on, Drug Y was
added to his therapeutic regimen. Which of the following can be expected?



A. Drug X will decrease the Vd of Drug Y

B. Drug Y will exhibit longer t1/2

C. Drug X will increase the protein binding of Drug Y

D. The therapeutic effect of Drug Y will decrease E. None of the above



Pharmacodynamics - ANSWER the study of the action of drugs within the body



Pharmacokinetics - ANSWER body to drug

toxicology - ANSWER the study of the poisonous effects of drugs

psology - ANSWER dose study

inducer - ANSWER increases metabolism, fast excretion of drugs, LOWER half-life,
lower therapeutic effect



inhibitor - ANSWER decrease metabolism, slow to none excretion, HIGHER half life,
higher therapeutic effect BUT TOXIC



Typical Antipsychotic - ANSWER act on DOPAMINERGIC system; blocks dopamine type
2 receptors



Atypical Antipsychotic - ANSWER act on SEROTONERGIC; particularly in 5-HT2A
(serotonin); lower affinity for dopaminergic receptors

, TRAP - ANSWER Parkinsons symptoms



Chlorpropamide - ANSWER Sulfonylurea with longest half-life; risk of hypoglycemia



N-acetyltransferase - ANSWER metabolism of HIPS is dependent on this phase II
enzyme



Acetylation - ANSWER HIPS are metabolized through



Alpha 2 - ANSWER adrenergic receptor exerts its action via inhibition of cAMP
production thru inhibition of adenylyl cyclase activity



Gs - ANSWER stimulates



Gi - ANSWER inhibits adenylate cyclase; inhibit conversion of ATP to cAMP



Gq - ANSWER increased IP3 and DAG (q as qontraction)



Nn & Nm - ANSWER ligand-gated Na channels



Hemicholinium - ANSWER inhibit reuptake of choline NOT storage



Vesamicol - ANSWER drug which acts on VESICULAR STORAGE of ACH



Sumatriptan - ANSWER serotonin agonist is best prescribed for relieve the symptom of
migraine



Triptans (5-HT B/D) - ANSWER Migraine

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