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Calcium Channel Blockers Questions with correct answers.
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Calcium Channel Blockers Questions with correct answers.
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Calcium Channel Blockers Questions with correctanswers
What are calcium channel blockers used to treat? Correct Answer-
Hypertension
Angina pectoris
Cardiac dysrhythmias
What is a controversy about calcium channel blockers? Correct Answer-
Safety for patients with hypertension and diabetes
What do verapamil and diltiazem act on? Correct Answer-Agents that
act on vascular smooth muscle and the heart
What does dihydropyridine act on? Correct Answer-Agents that act
mainly on vascular smooth muscle
What are the effects of calcium channel blockers on vascular smooth
muscle? Correct Answer-Calcium channels open = Contractile process
Calcium channels blocked = Vasoconstriction
What are the therapeutic doses of calcium channel blockers? Correct
Answer-Selectively act on peripheral arterioles and arteries and
arterioles of the heart
No significant effect on veins
, What parts of the heart do calcium channel blockers act on? Correct
Answer-Myocardium
Sinoatrial (SA) node
Atrioventricular (AV) node
Coupling of cardiac calcium channels to beta1-adrenergic receptors
What are the classifications of calcium channel blockers? Correct
Answer-Dihydropyridines: Nifedipine
Phenylalanine: Verapamil
Benzothiazepine: Diltiazem
What are the sites of action of calcium channel blockers? Correct
Answer-Dihydropyridines act primarily on arterioles
Verapamil and diltiazem act on arterioles and on the heart
What are the hemodynamic effects of Verapamil and Diltiazem? Correct
Answer-Direct effects on the heart and blood vessels
Indirect (reflex) effects
Net effects
What are the 5 hemodynamic effects of Verapamil and Diltiazem?
Correct Answer-Blockade at peripheral arterioles
---Reduces arterial pressure
Blockade at arteries and arterioles of heart
---Increases coronary perfusion
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