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BSN 315 Pharm II Week 12 Antivirals Questions With Complete Solutions
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BSN 315 Pharm II Week 12 Antivirals Questions WithComplete Solutions
Abacavir is indicated for HIV infection and prophylactically
after occupational HIV exposure.
abacavir inhibits reverse transcriptase, an enzyme needed by the
HIV to replicate itself. Correct Answer Efavirenz binds to and
later alters reverse transcriptase, an enzyme needed by the HIV
to replicate itself.
Efavirenz is indicated for use with other antiretrovirals to treat
HIV-1 virus.
Efavirenz is an NNRTI that should be taken on an empty
stomach. However, capsules may be opened and sprinkled in a
small amount of food. No other food should be taken within 2
hours of administration.
Antiviral and Antiretroviral Therapy
Oseltamivir is approved for the prevention and treatment of
influenza in persons 1 year and older. The drug inhibits viral
replication and shortens duration of influenza. It should be
started within 48 hours of influenza symptoms.
Patient Safety
Hydration is important while taking oseltamivir. Correct
Answer Acyclovir is a synthetic purine nucleoside analog and is
the drug of choice to treat infections caused by members of the
herpesvirus family.
Acyclovir inhibits viral DNA synthesis. It also inhibits the
activity of HSV-1 HSV-2, and varicella zoster.
Acyclovir is used to treat encephalitis, herpes genitalis and
labialis, herpes zoster, varicella, and complicated infection with
herpes simplex virus.
,Case Study
Mr. Zeke, a 32-year-old male patient, is admitted to the hospital
with complaints of redness and itching in the genital area. Upon
inspection the nurse notices several small blisters in the patient's
perineum. The health care provider makes a diagnosis of genital
herpes simplex and prescribes acyclovir. Mr. Zeke has a history
of a kidney transplant and is taking immunosuppressant
medications. The patient's vital signs are blood pressure =
110/60 mm Hg, pulse = 72 beats per minute, and temperature =
100.00°F. Mr. Zeke is sexually active and does not use
protection during intercourse. Correct Answer
Cobicistat is used in conjunction with antiretrovirals to improve
the effectiveness of antiretroviral drugs. Correct Answer
Maraviroc blocks CCR5 coreceptors on the surface of certain
immune cells, preventing HIV from entering the cell.
Maraviroc is the only approved CCR5 antagonist for the
treatment of patients of CCR5-tropic HIV. Maraviroc is not
effective against other strains of HIV. Correct Answer
Raltegravir blocks HIV integrase, an enzyme needed by HIV to
replicate itself.
Raltegravir was the first HIV integrase strand inhibitor that
slows the advancement of HIV infection.
Question 1 of 18
For which patient would oseltamivir be appropriate in the
treatment of influenza?
6-month-old patient who has been sick for 24 hours
12-month-old patient who has been sick for 4 days
, 6-year-old patient who has been sick for 36 hours
30-year-old patient who has been sick for 7 days Correct
Answer 6-year-old patient who has been sick for 36 hours
Oseltamivir is approved for persons 1 year old and older and
should be started within 48 hours of influenza symptoms.
Question 1 of 4
Which preadministration assessment is most important for Mr.
Zeke, who is diagnosed with herpes genitalis?
Vital signs
Hydration
Renal function
Determination of exposure to close acquaintances Correct
Answer Renal function
Mr. Zeke has had a kidney transplant and is taking an
immunosuppressant. The nurse needs to be aware of potential
drug-drug interactions. Increase in nephrotoxicity can occur with
other nephrotoxic drugs, such as immunosuppressants. Caution
is advised in administering acyclovir to a patient with renal
impairment.
Question 1 of 4
Which statement is accurate with respect to the goal of antiviral
treatment for viral hepatitis B (HBV)?
To reduce or suppress liver inflammation
To kill all HBV
To enhance the patient's immune system
To sequester HBV for elimination Correct Answer To reduce
or suppress liver inflammation
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