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Summary GTS161 theme 5 notes R50,00
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  3. University Of Pretoria (UP)
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  5. GTS161 (GTS161)

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Summary GTS161 theme 5 notes
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These notes are a 2-page summary of GTS161 theme 5. They provide a detailed but concise overview of the lecture notes with colour images to aid understanding. They were written by a student who obtained a distinction in the module.

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  • October 10, 2024
  • 2
  • 2023/2024
  • Summary

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Theme 5
Defini&ons
• Pedigree - pictorial representa&on of a family history, family tree that outlines the
inheritance of one or more trait
• Proband - person from whom the pedigree is ini&ated




Autosomal recessive traits
• in both sexes with = frequency
• skip genera&ons
• affected offspring to unaffected parents
• Appears more frequently among the children of consanguineous marriages
Autosomal dominant
• both sexes with = frequency
• does not skip genera&ons
• unaffected parents do not transmit the trait
X-linked recessive
• more males than females affected
• affected sons born to unaffected mothers
• skips genera&on
• half of carrier mother sons ara affected
• NEVER passed from father to son
• daughters of affected fathers are carriers
X-linked dominant
• more females than males affected
• does not skip genera&ons
• affected sons = affected mother
• affected daughters = affected mother or father
• affected fathers to all daughters
Y-linked traits
• ONLY males
• father to all sons
• does not skip genera&ons
Twins
• Dizygo&c twins - non iden&cal twins (2 separate eggs are fer&lized by 2 different
sperm)(50% of genes alike)

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