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Exam (elaborations)

NURG 5710 Pharm Module 1 Questions and Answers (100% Pass)

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  • Course
  • NURG 5710
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  • NURG 5710

PHARMACODYNAMICS the study of the effects of drugs on the body PHARMACOKINETICS the study and analysis of the time course of the drug in the body; individual patient's ability to absorb, distribute, metabolize, and eliminate the drug CHEMICAL NAME The name of a chemical compound that sh...

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  • October 12, 2024
  • 61
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NURG 5710
  • NURG 5710
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1 | P a g e | © copyright 2024/2025 | Grade A+




NURG 5710 Pharm Module 1
Questions and Answers (100% Pass)
PHARMACODYNAMICS


✓ the study of the effects of drugs on the body




PHARMACOKINETICS


✓ the study and analysis of the time course of the drug in the body;

individual patient's ability to absorb, distribute, metabolize, and

eliminate the drug




CHEMICAL NAME


✓ The name of a chemical compound that shows the names of each of

its elements or sub-compounds. For example, the chemical name of

aspirin is acetylsalicylic acid.




GENERIC/NON-PROPRIETARY NAME


✓ a short name coined for a drug or chemical not subject to proprietary

(trademark) rights and recommended or recognized by an official

body




Master01 | October, 2024/2025 | Latest update

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TRADE NAME


✓ a brand name or trademark under which a proprietary product is

marketed




ABSORPTION


✓ the movement of a drug from it's site of administration into the blood;

influenced by cell membrane, blood flow at administration site, drug

solubility, molecular weight, drug concentration




BIOAVAILABILITY


✓ the amount of drug dose that reaches the systemic circulation




PASSIVE DIFFUSION


✓ simple diffusion of drug from areas of high concentration to areas of

lower concentration




ACTIVE TRANSPORT


✓ molecule is actively transported across cell membranes, often via the

ATP pump




VOLUME OF DISTRIBUTION

Master01 | October, 2024/2025 | Latest update

, 1 | P a g e | © copyright 2024/2025 | Grade A+

✓ (Vd) a mathematically determined measure of the size of a

compartment that would be filled by the amount of a drug in the same

concentration found in the blood or plasma; useful in expressing affinity

of a drug to tissue and storage sites and in calculating a drug's

clearance from the body; larger volume of distribution indicates larger

dose should be administered to achieve a target concentration




METABOLISM


✓ the process of chemically changing a drug to a different compound

called a metabolite; the enzymatic alteration of drug structure to

enhance excretion, inactivate, increase therapeutic action, activate a

prodrug, increase or decrease toxicity




P450 CYTOCHROME


✓ a clinically significant oxidation enzyme involved in drug metabolism




PHASE I REACTION


✓ chemical reactions seen in drug metabolism such as oxidation,

reduction, and hydrolysis




PHASE 2 REACTION



Master01 | October, 2024/2025 | Latest update

, 1 | P a g e | © copyright 2024/2025 | Grade A+

✓ synthetic or conjugation reactions, involve the attachment of another

chemical group to a drug, resulting in a chemical with greater water

solubility needed for elimination




FIRST PASS METABOLISM


✓ drugs metabolized in liver before travelling to site of action or after

they have been to the site of action




HALF LIFE


✓ the amount of time it takes to eliminate one half of the drug from the

body; determines how often a drug is administered; important variable

for estimating time to reach steady state plasma concentration after

change of maintenance dose, estimating time required to eliminate all

or portion of discontinued drug from the body, predicting plasma levels

after initiation of therapy, determining dose interval needed to provide

desired fluctuation in plasma concentration during that interval,

determining the fluctuation in plasma concentrations, given a specific

dosing interval




ELIMINATION


✓ removal of the drug from the body by organs of elimination




Master01 | October, 2024/2025 | Latest update

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