Biology Terminology
DNA
DNA - Made up of 2 strands/nucleic acids wrapped around to form a double Helix.
Nucleotide – The building block of nucleic acids. Consists of: Phosphate, Deoxyribose sugar &
Nitrogenous base.
Nitrogenous base – Have complementary pairs.
– Purine bases: Have 2 Carbon rings (BIG) -> A & G
– Pyrimidine bases: Have 1 Carbon ring (SMALL) -> T & C
– Names of Nitrogenous bases: Adenine (A)
Guanine (G)
Cytosine (C)
Thymine (T)
Uracil (U)
RNA
– Shorter than DNA
– Single stranded
– Contains Ribose sugar instead of Deoxyribose sugar.
mRNA – Messenger RNA
– Carries the instructions from DNA about which amino acids will be in a polypeptide.
tRNA – Transfer RNA
– Transports amino acids to the ribosome to create an amino acid chain.
Protein Synthesis – Process of making proteins in a cell.
Transcription – Occurs in the nucleus.
– Where DNA is being converted into mRNA.
Translation – mRNA strand is translated into a string of amino acids.
Codon – A triplet of nitrogenous bases on a piece of mRNA that codes for a particular amino
acid.
Anti-Codon – Sequence of 3 nucleotides forming a unit of genetic code in a tRNA molecule,
corresponding to the complementary codon in mRNA.
Amino acids – Monomer of proteins.
mtDNA – Mitochondrial DNA. Passed down from one’s mother only, found in the
mitochondria.
Gene – Sequence of nucleotides on a chromosome that codes for a particular trait/protein.
DNA Replication – Process which produces an exact copy of a DNA molecule (i.e. replicates).
– Occurs during interphase. – Occurs only in the nucleus.
– Purpose is to prepare cell for mitosis or meiosis.
DNA profiling – Purpose: -> To identify samples (blood, semen, skin cells, root hair – must
have a nucleus).
-> Forensics/solving crimes, paternity test, missing ppl, certain genetic diseases.
, – Steps: -> PCR (Polymerase Chain Reaction): Used to amplify (make more of) the DNA.
-> Restriction enzymes: Cut DNA into fragments.
-> Gel electrophoresis: - Separates out the bands so that DNA fingerprints can be compared.
- DNA bands separated according to size, using electric current.
Non-coding DNA – Sequence of nucleotides on a chromosome that DOES NOT code for a
particular trait. Used in DNA fingerprinting.
MEIOSIS
Meiosis – Meiosis is a form of cell division whereby haploid gametes are formed that are
genetically non-identical.
Homologous pair – Paired chromosomes that are the same size, same shape & same gene at
the same locus.
Haploid (n) – Half complement of chromosomes.
Diploid (2n) – Full complement of chromosomes.
Reduction division – Number of chromosomes formed halved.
Gametes – Sex cells.
Crossing over – Results in recombination of alleles for variation. Occurs in Prophase 1.
Random assortment – When chromosomes (OR replicated chromosomes) line up at equator
in no particular order. (Occurs in either Metaphase 1 or Metaphase 2)
Chiasma/Chiasmata – Point where chromatids cross.
Non-disjunction – Failure of chromosomes to separate during Anaphase 1 or Anaphase 2.
Karyotype – Picture of chromosome.
Aneuploidy – Occurs when there is 1 extra (trisomy) or 1 missing (monosomy) chromosome.
Polyploidy – Occurs when there is many extra SETS of chromosomes.
GENETICS
Gene – Sequence of nucleotides on a chromosome that codes for a particular trait/protein.
E.g., eye colour.
allele – Alternate form/Variation of the gene. E.g., blue, brown, green, hazel.
locus – Position or location of the gene on the chromosome.
Heterozygous – When a person inherits different alleles for a gene pair. E.g., Rr, Bb, Tt.
Homozygous dominant: When a person inherits both dominant alleles for a gene pair. E.g.,
RR, BB, TT.
Homozygous recessive – When a person inherits both of the (same) recessive alleles for a
gene pair. e.g., rr, bb, tt.
Dominant – The trait that is expressed when in a heterozygous condition.
Recessive – The trait that will only be expressed if a person inherits both alleles.
Phenotype – Physical makeup of the individual.
P1 – First generation of parents.
Genotype: Genetic makeup of individual for that gene.
Genome – Complete set of genes of a particular organism.
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