Class notes
Biochemistry TCA Cycle Lecture
- Institution
- University Of The Witwatersrand (wits)
- Book
- Biochemistry
These notes contain the material covered during the lecture, they are not a complete summary of the textbook chapter.
[Show more]
Connected book
Book Title:
Author(s):
- Edition:
- ISBN:
- Edition:
Seller
Follow
Content preview
TCA cycleGlucose potential energy
aYycolyn f small E releate
TEAcycle little more E release
ETO MOST E released process Oxidative phosphorylation
Remember Atp formed a ADP phosphorylation 2ways
offidatrbh
phosphorylation phosphorylatio
substrate
level
summaryaerobic E production
pyruvate
coz Decarboxylation nun
Acetyl CoA
U
TCAcycle
o
E released oxidativeproceso
form coenzymes NADH
FADH2
e given coenzymes s Eto s 02 final e
acceptor acceptor
molecules
etransfer createproton gradientaccroromembrane
stored E drives ATPrynthetis
ETO oxidativephot ATPsynthesized
ufque
I glucote 2 glycolyn't
go zg Ayp 2TUA
INA ET O
Mon E created during oxidativephotphorylation
,24 e removed complete oxidation glucose
Glycolyn V 2ATP
4C 2e from 2 NADH's
1 pyruvate decarboxylation 2e X 2 pyruvate 4 e
TCA g gleATP x z benpyruvate
ETO 8C 202
t 41120 X 2
1Glucose 24e El 30 38 ATP
TCA enzyme8 Matrix mitochondria
EXCEPT tuccinatedehydrogenate
integralmembrane
protein linked to
innermitochondrial
membrane
, pyruvate source AcetylCoA
glycolytic pyruvate AcetylcoA 1A
cytoplasm oxidative carboxylation mitochon
before enteromitochon
4
Enzyme pyruvateDehydrogenasecomplex Pbo
Complex
pyruvate Coat NADt s Acetyl CoA COLT NADH Ht
RxnMech PDO
pyruvateDehydrogenase
3Enzymed Dihydrolipoamide acetyltransferase
Dihydrolipoamide dehydrogenase 1849
5 coenzyme8 Thiamine pyrophosphate
GASH
FAD
NAD
Lipoiona'd
mech pyruvate Decarboxylated
L CO2
20 unit transfer to lipoicacid
e
t ormfarfimnfEfyfaflipaa.cl
2Cunitlipacid WASH
Re oxidation Lipoivacid
allow mech repeat
NADHproduced enters ETO
(Garret and Grisham,
2016)
El EL E3
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through EFT, credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying this summary from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller lmvw. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy this summary for R50,00. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
52355 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy summaries for 14 years now