Medical biosciences - Study guides, Study notes & Summaries

Lecture notes from Imperial College London, Medical Biosciences BSc, 2nd year, genetics and genomics (GEN) module. "In this last session we will review new and emerging methods, such as single cell sequencing and CRISPR-based genome engineering, and see how they are set to transform areas such a gene therapy, personalised medicine, ageing and the use of non-human organisms. We will also touch on the potential risks and ethical issues raised by these developments." learning objectives: ...

Lecture notes from Imperial College London, Medical Biosciences BSc, 2nd year, genetics and genomics (GEN) module. Focus on genomic DNA. How do we know it is the DNA that genes are made of? In fact, for a long time it was thought that genes must be made of protein. We'll describe how this idea was disproved. Once it was realised that genes were DNA, techniques for analysing DNA burgeoned and gave rise to modern molecular genetics and genomics. We will review the basic principles of some of t...

Lecture notes from Imperial College London, Medical Biosciences BSc, 2nd year, genetics and genomics (GEN) module. These notes describe the ways in which genetic linkage maps and physical maps are generated and combined. I describe Genome-Wide Association Studies, which compare the genome sequences of many individuals in distinct populations, in order to locate regions that determine multi-genic phenotypes such as height or diabetes. learning objectives: - Explain the principles of link...

Lecture notes from Imperial College London, Medical Biosciences BSc, 2nd year, pharmacology module. Phar 9 on obesity: In this session, we will turn our attention to a different challenge: pharmaceuticals for treating obesity. We will start by defining what we mean by the term obese, before considering the fundamental causes, and pharmacologically-relevant mechanisms that contribute to obesity. Later, we will explore pharmaceuticals that are in use (or have previously been used) to treat o...

Lecture notes from Imperial College London, Medical Biosciences BSc, 2nd year, pharmacology module. Phar 9 on obesity: In this session, we will turn our attention to a different challenge: pharmaceuticals for treating obesity. We will start by defining what we mean by the term obese, before considering the fundamental causes, and pharmacologically-relevant mechanisms that contribute to obesity. Later, we will explore pharmaceuticals that are in use (or have previously been used) to treat o...

Lecture notes from Imperial College London, Medical Biosciences BSc, 2nd year, pharmacology module. Phar 9 on obesity: In this session, we will turn our attention to a different challenge: pharmaceuticals for treating obesity. We will start by defining what we mean by the term obese, before considering the fundamental causes, and pharmacologically-relevant mechanisms that contribute to obesity. Later, we will explore pharmaceuticals that are in use (or have previously been used) to treat o...

Lecture notes from Imperial College London, Medical Biosciences BSc, 2nd year, Neuroscience (NEU) module. Learning is the acquisition of new knowledge and skills. Memory is the retention of learned information. We learn and remember lots of different things and it is important to appreciate that these various things might not be processed and stored by the same neural hardware. No single brain structure or cellular mechanism accounts for all learning. Moreover, the way in which information of...

Lecture notes from Imperial College London, Medical Biosciences BSc, 2nd year, cardiovascular and thoracic biology (CTB) module. Lecture 5 on some of the techniques that we can use to evaluate the way the heart and lungs are working. These techniques are routinely used in the clinical evaluation of patients, and also in a performance setting where athletes are trying to make small gains in performance. In particular, we’ll explore exercise and how control of cardiopulmonary function changes...

Lecture notes from Imperial College London, Medical Biosciences BSc, 2nd year, pharmacology module. Phar 3 on psychoactive drugs, depressants (alcohol, cannabis): - Lipid solubility: Predict how the lipid solubility of alcohol and cannabis will influence drug distribution. - Dosing: Calculate the amount of alcohol administered within specific doses and predict the likely bioavailability associated with each dose. - Pharmacokinetics: Compare and contrast how alcohol and cannabis are abso...

Lecture notes from Imperial College London, Medical Biosciences BSc, 2nd year, Neuroscience (NEU) module. Vocabulary neurology + list of classical syndromes and damages.