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Class notes

Evolutionary Genetics Selection and Lactose Persistence

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The notes provide details on the following: General Introduction What is lactase persistence / where is it seen? Lactose persistence and selection in African populations Molecular methods used to find SNPs in African populations How to detect selection & calculate when selection occurred

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  • July 16, 2023
  • 42
  • 2022/2023
  • Class notes
  • Dr colleen o’ryan
  • All classes
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kayladamon36
EVOLUTIONARY GENETICS




Dr Colleen O’Ryan
colleen.oryan@uct.ac.za

,General Introduction


2

, Read Revision Notes
Read Tischkoff et al paper


• Try to do this ASAP, esp the Tishkoff
paper
• This will allow to engage better with the
next few lectures

, Welcome to the Evolutionary Genetics Module

WHAT IS EVOLUTIONARY GENETICS?

“Evolutionary genetics is the broad field of studies that examines
evolution in terms of changes in gene & genotype frequencies within
populations, and the processes that convert the variation within
populations into permanent variation observed between species”.




4

, Broad themes covered in this module
1. Introduction:
Self-Revision - notes separately loaded to VULA


2. Selection in human populations
Lactose persistence & pigmentation


3. Selection - Epigenetics
Feeding behaviour (diet)


4. Behavioural genetics
Animal models & human examples



5

, WHAT IS LACTASE PERSISTENCE / WHERE IS
IT SEEN?



6

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