Mtx - Study guides, Study notes & Summaries

Methotrexate CORRECT ANSWER Uses: Lymphocytic leukemia, lymphomas, sarcomas - Practice: High dose MTX (over 200 mg/m2) causes bone marrow toxicity, use leucovorin "rescue" 12-24 hours after MTX infusion; potential for renal toxicity, push fluids; may cause photosensitivity - Side Effects: Leukopenia or Thrombocytopenia, Stomatitis (with increase doses), nephrotoxicity Cytarabine (Cytosar-U) CORRECT ANSWER Uses: Hodgkin's and Non-Hodgkin's Lymphoma; leukemia (acute, non-lymphocytic/ac...

What is the genetic inheritance pattern of Hemophilia A? - correct answer X-linked recessive: women born to fathers with X linked recessive disorder will be carriers. Males are 50% carriers if born to an affected mother. What is tx of Lewy body dementia? - correct answer Dopamine agonist therapy (PD) & AchE inhibitors (Alzeihmer's) - watch for dopamine agonist therapy causing complex visual hallucinations. A patient treated for LTBI and now has positive PPD. Asymptomatic and also has ...

CPHON Exam 195 Questions with Verified Answers Classification of Methotrexate - CORRECT ANSWER antimetabolite (s-phase) Classification of mercaptopurine and thioguinine - CORRECT ANSWER antimetabolite(s-phase) Classification of fludarabine/nelarabine - CORRECT ANSWER anti-metabolite Classification of cytarabine/gemcitabine - CORRECT ANSWER antimetabolite Classification and sub-class of ironotecan/topotecan - CORRECT ANSWER Topoisomerase inhibitors (campotothecins) Classificatio...

Key drugs that can cause hypothyroidism - ANSWER-"I TALC" Interferons Tyrosine Kinase Inhibitors Amiodarone Lithium Carbamazepine Conditions: Hashimoto's disease Levothyroxine IV:PO - ANSWER-0.75:1 (IV:PO) Full replacement dose levothyroxine - ANSWER-1.6 mcg/kg/day (IBW) If known CAD: start with 12.5-25 mcg daily Levothyroxine tablet colors - ANSWER-Orangutans Will Vomit On You Right Before They Become Large Proud Giants 25 Orange 50 White (no dye) 75 Violet 88 Olive 10...

Ob/Gyn Shelf Exam Questions and Answers 100% Pass Rx for advanced (Stages II ) ovarian cancer - Answer- Surgical removal, followed by adjuvant chemo (taxane carboplatin) When is magnesium sulfate given for preeclampsia? - Answer- During delivery and 24 hours postpartum Therapeutic level of mag sulfate - Answer- 4-7 Mag sulfate levels associated with respiratory depression and cardiac arrest - Answer- >12 and >15 Contraindications to expectant management of severe preeclampsia (e.g....

What is the genetic inheritance pattern of Hemophilia A? - correct answer X-linked recessive: women born to fathers with X linked recessive disorder will be carriers. Males are 50% carriers if born to an affected mother. What is tx of Lewy body dementia? - correct answer Dopamine agonist therapy (PD) & AchE inhibitors (Alzeihmer's) - watch for dopamine agonist therapy causing complex visual hallucinations. A patient treated for LTBI and now has positive PPD. Asymptomatic and also has ne...

how often do you screen for hypothyroidism after > 35 YO every 5 years T4 Levothyroxine T3 Liothyronine Subclinical TSH range 5-9 Starting dose Levothyroxine in healthy adult 1.6 mcg/kg/day If elderly or CAD what is the starting dose levothyroxine 12.5-25 mcg/day Amiodarone can induce ____thyroidism in iodine deficiency hyperthyroidism TSH offers positive/negative feedback from _____ gland pituitary Definitive treatment for hyper...

Chemo Certification Practice Test 2024/2025 Questions and Answers 100% Solved Totect - Anecdote for Doxorubicin Warm Compress - Plant alkaloids and etoposide Bleomycin - bad for the lungs Leucovorin - potentiates the effects of 5-FU and decreases the effect of MTX Calvert Formula Components - Area under the curve (AUC) Carboplatin Creatinine Clearance Aromatase Inhibitors - used for postmenopausal women- osteoporosis Vesicant Administration - Prior to non-vesicant drugs Th...

CPHON Examples of Alkylating Agents - correct answer Carboplatin, Cisplatin, Carmustine, Lomustine, Cytoxan, Ifosfamide, Melphalan, Temozolomide, Thiotepa Examples of Antimetabolites (Cell-cycle Specific) - correct answer MTX, 5-FU, ARA-C, 6-MP, 6-TG Examples of Plant Detrivatives (Cell-cycle Specific) - correct answer Etoposide, irinotecan, vincristine Examples of Antibiotics for Cancer treatment - correct answer Dactinomycin, Bleomycin Examples of Anthracyclines - correct answer D...

Examples of Alkylating Agents - Answer Carboplatin, Cisplatin, Carmustine, Lomustine, Cytoxan, Ifosfamide, Melphalan, Temozolomide, Thiotepa Examples of Antimetabolites (Cell-cycle Specific) - Answer MTX, 5-FU, ARA-C, 6-MP, 6-TG Examples of Plant Detrivatives (Cell-cycle Specific) - Answer Etoposide, irinotecan, vincristine Examples of Antibiotics for Cancer treatment - Answer Dactinomycin, Bleomycin Examples of Anthracyclines - Answer Doxorubicin, Daunorubicin Misc chem...