Transcription factor Study guides, Study notes & Summaries

BIO 100 EXAM 2 STUDY GUIDE LATEST UPDATE GRADED A+ What characteristic of DNA evidence makes it particularly valuable in criminal investigations? Its uniqueness to each individual organism. What ensures the stability of the complementary base pairs in a DNA molecule? Hydrogen bonds. Why did the double helix model of DNA generate excitement in the scientific community? It elucidated how genetic material could be duplicated through complementary strands. What are the alternative ...

NBME PHYSIOLOGY UPDATED EXAM WITH COMPLETE SOLUTIONS 2023/2024 Prostglandin - CORRECT ANSWER-From mast cells, macrophages, EC, and platelets Vasodilation, pain Rate controlling step in Insulin secretion - CORRECT ANSWER-Phosphorylation of glucose by glucokinase Glucokinase mutation - CORRECT ANSWER-Autosomal dominant form of early onset type 2 diabetes GLUT 2 - CORRECT ANSWER-low affinity high capacity glucose transporter. Uptake by beta cells Insulin release - CORRECT ANSWER-Bloo...

CMMB 403 Midterm 1 Question and answers 100% correct CMMB 403 Midterm 1 Describe the RTK signal transduction pathway when activated by the FGF ligand FGF ligand dimerizes RTK receptor. Receptor is phorphorylated and attracts adaptor/GEF. GEF begins phosphorylation cascade: GEF to Ras to Raf to Mek to Erk to TF. TF transcribes gene Describe the JAK-STAT pathway when activated by FGF FGF ligand dimerizes RTK. JAK2 proteins cross-phosphorylate. Both JAK2s phosphorylate a STAT5 (which is...

What is gene expression? ~~> dsDNA is decoded to ssRNA/proteins by an mRNA intermediate using A/U/C/GTPs and RNA polymerase Where is the consensus sequence in prokaryotic promoters? ~~> at -10 and -35 upstream of the the transcription start site What recognises the consensus sequences in prokaryotes? ~~> the holoenzyme What is a holoenzyme? ~~> a closed complex with a core enzyme and sigma factor 70 What does the holoenzyme do? ~~> causes the dsDNA to open and allo...

Eukaryotic promoters have a basal region which can contain a TATA box, initiator (Lnr), BRE (TFIIV recognition element) and what other element? ~~> Downstream core promoter (DPE) In prokaryotes RNA polymerase requires what co-factor? ~~> 70 sigma factor Forms the holoenzyme The promoter is formed of two hexameric sequences at what positions? ~~> -35 and -10 The amount of product transcribed is dependant on how close the promoter sequences are to what? ~~> Consensus s...

Test Bank Porth Pathophysiology Concepts of Altered Health States 2nd Canadian EditionTable of Contents Chapter 01: Concepts of Health and Disease .......................................................................................................... 2 Chapter 02: Concepts of Altered Health in Children ............................................................................................. 13 Chapter 03: Concepts of Altered Health in Older Adults ............................................

TEST BANK PATHOPHYSIOLOGY THE BIOLOGICAL BASIS FOR DISEASE IN ADULTS AND CHILDREN BY McCance Chapter 1: Cellular Biology MULTIPLE CHOICE 1. Which statement best describes the cellular function of metabolic absorption? a. Cells can produce proteins. c. Cells can take in and use nutrients. b. Cells can secrete digestive enzymes. d. Cells can synthesize fats. ANS: C In metabolic absorption, all cells take in and use nutrients and other substances from their surroundings. The remaini...

Ras signaling - GTPase - promotes growth and proliferation - mutated in 20-30% of all cancers - point mutations are most common G12V mutation - blocks GAP binding - locks RAS in active state, promoting proliferation Q61K mutation - raises activation energy of GTP hydrolysis - blocking hydrolysis, keeping RAS active Hallmarks of cancer 1) self-sufficiency in growth signals 2) insensitivity to anti-growth signals 3) unstable DNA 4) metastasis 5) evasion of apoptos...

Histone acetylase Correct Answer adds acetyl group onto lysine to remove charge to loosen DNA packaging Changes histones into open conformation and allows for DNA folding and transcription Concentrations influenced by hormones Hepcidin Correct Answer a hormone produced by the liver that negatively regulates iron balance in the gastrointestinal tract Brefeldin A Correct Answer Inhibits Golgi function and secretion of hormones Used to study hormone build-up Coat associated protei...

CPHON Exam 93 Questions with Verified Answers G1 - CORRECT ANSWER The first gap, or growth phase, of the cell cycle, consisting of the portion of interphase before DNA synthesis begins. Cell grows larger and produces ribosome and proteins. S - CORRECT ANSWER All 46 chromosomes are replicated in the cells nucleus G2 - CORRECT ANSWER The second gap, or growth phase, of the cell cycle, consisting of the portion of interphase after DNA synthesis occurs. DNA is condensed into rod form . (...